Trial of cromoglycate and slow-release aminophylline in perennial childhood asthma.
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چکیده
منابع مشابه
Controlled trial of slow-release aminophylline in childhood asthma: are short-term trials valid?
Slow-release aminophylline, although widely used for the prophylaxis of childhood asthma, has had only limited formal assessment. A four-month double-blind cross-over trial of slow-release aminophylline (14 mg/kg twice daily) was carried out in 24 children with perennial asthma. Satisfactory serum theophylline concentrations were obtained in 17 children, with few side effects. There was a signi...
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tifen and placebo and prophylaxis of asthma in young children. Br J Dis Chest 1984;78:163-7. 2 Phelan PD, Landau LI, Olinsky A, (eds). Respiratory illness in children. Oxford: Blackwell Scientific Publications, 1982:186. 3 Hambledon G, Weinberger M, Taylor J, et al. Comparison of cromoglycate and theophylline in controlling symptoms of chronic asthma. Lancet 1977;i:381. 4 Ellis PE, Koysooko R, ...
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In a double-blind controlled trial 14 chronic asthmatic patients with regular nocturnal exacerbations took 16 mg slow-release oral salbutamol (two Ventolin spandets), 450 mg slow-release aminophylline (two Phyllocontin Continus tablets), or placebo at midnight. Mean peak expiratory flow rates on waking were significantly higher on the active drugs than on placebo (p < 0.01 for salbutamol; p < 0...
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A double-blind, cross-over study was undertaken to compare inhalation of betamethasone valerate (BV, 800 microgram daily) with sodium cromoglycate (SCG, 80 mg daily) in twenty children requiring bronchodilators for perennial asthma. Each treatment period lasted 4 weeks but statistical comparisons were made only in respect of the last 14 days of each therapy. When the children were using BV they...
متن کاملComparison of actions of disodium cromoglycate and ketotifen on exercise-induced bronchoconstriction in childhood asthma.
Ketotifen (Zaditen), a benzocycloheptathiophene derivative, is a new oral agent for treating asthma, with action similar in some respects to that of sodium cromoglycate. It is well established that sodium cromoglycate protects against antigen challenge by inhibiting the release of chemical mediators from mast cells. It also inhibits exerciseinduced bronchoconstriction and has bronchodilator pro...
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عنوان ژورنال:
- British medical journal
دوره 281 6244 شماره
صفحات -
تاریخ انتشار 1980